CMap Candidate Details

Structure:
CMap ID: C00871
Pert ID: BRD-A35519318
Compound Name: benidipine
Targets: CACNA1C; CACNA1G
MoA: Calcium channel blocker
SMILES: COC(=O)C1[C@H](C(=C(C)N=C1C)C(=O)O[C@@H]2CCCN(Cc3ccccc3)C2)c4cccc(c4)[N+](=O)[O-]
InchiKey: VATGWEZOSFWWCV-SKWHODKYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
24378 BRD-A35519318 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24523 BRD-A35519318 A549 10 uM 24 h -0.2 -0.83 0.0 -0.33 -1.12 0.93
24716 BRD-A35519318 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24839 BRD-A35519318 HT29 10 uM 6 h 0.0 0.0 0.0 -0.21 -0.69 0.03
25065 BRD-A35519318 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.93 0.36
25127 BRD-A35519318 PC3 10 uM 24 h 0.0 0.0 0.0 0.23 0.83 0.11
25287 BRD-A35519318 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).