CMap Candidate Details

Structure:
CMap ID: C00872
Pert ID: BRD-A35588707
Compound Name: teniposide
Targets: TOP2A
MoA: Topoisomerase inhibitor
SMILES: COc1cc(cc(OC)c1O)[C@H]1[C@@H]2C(COC2=O)C(O[C@@H]2O[C@@H]3CO[C@H](OC3[C@H](O)[C@H]2O)c2cccs2)c2cc3OCOc3cc12
InchiKey: NRUKOCRGYNPUPR-OQMCATNJSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9286 BRD-A35588707 AGS 1.25 uM 6 h -0.22 -0.9 0.04 0.27 0.96 0.34
9590 BRD-A35588707 H1299 1.25 uM 6 h 0.0 0.0 0.0 0.28 0.98 0.38
9907 BRD-A35588707 HA1E 1.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10286 BRD-A35588707 HCC515 1.25 uM 6 h 0.0 0.0 0.0 -0.41 -1.36 2.02
10395 BRD-A35588707 HCT116 1.25 uM 6 h 0.0 0.0 0.0 -0.2 -0.66 0.01
10903 BRD-A35588707 HT29 1.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11248 BRD-A35588707 MCF??7.00 1.25 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11337 BRD-A35588707 NCIH2073 1.25 uM 6 h -0.25 -1.05 0.23 0.0 0.0 0.0
11908 BRD-A35588707 NCIH596 1.25 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12205 BRD-A35588707 NOMO1 1.25 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12475 BRD-A35588707 PC3 1.25 uM 24 h 0.28 1.16 0.34 0.23 0.81 0.09
12663 BRD-A35588707 SW480 1.25 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12990 BRD-A35588707 THP1 1.25 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13142 BRD-A35588707 U937 1.25 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13532 BRD-A35588707 VCAP 1.25 uM 6 h -0.25 -1.05 0.24 0.0 0.0 0.0
39043 BRD-A35588707 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39270 BRD-A35588707 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39564 BRD-A35588707 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39890 BRD-A35588707 HEPG2 10 uM 6 h -0.28 -1.18 0.51 0.3 1.05 0.57
40989 BRD-A35588707 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41313 BRD-A35588707 SKB 10 uM 24 h 0.0 0.0 0.0 0.33 1.15 0.89
96016 BRD-A35588707 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).