CMap Candidate Details

Structure:
CMap ID: C08802
Pert ID: BRD-K20141153
Compound Name: atomoxetine
Targets: SLC6A2; SLC6A3; SLC6A4
MoA: Norepinephrine transporter inhibitor
SMILES: CNCC[C@@H](Oc1ccccc1C)c1ccccc1
InchiKey: VHGCDTVCOLNTBX-QGZVFWFLSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2994 BRD-K20141153 HA1E 10 uM 6 h 0.0 0.0 0.0 0.29 1.01 0.44
3157 BRD-K20141153 HCC515 10 uM 24 h 0.0 0.0 0.0 0.26 0.93 0.27
3744 BRD-K20141153 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44545 BRD-K20141153 A549 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.78 0.09
45196 BRD-K20141153 HEPG2 10 uM 6 h -0.25 -1.06 0.25 0.0 0.0 0.0
120857 BRD-K20141153 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120940 BRD-K20141153 HEK293 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120997 BRD-K20141153 HELA 0.04 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
121032 BRD-K20141153 MCF??7.00 0.125 uM 24 h 0.22 0.91 0.03 0.0 0.0 0.0
121098 BRD-K20141153 YAPC 0.37 uM 24 h 0.0 0.0 0.0 -0.33 -1.1 0.86
129184 BRD-K20141153 HT29 0.01 uM 24 h 0.0 0.0 0.0 -0.29 -0.97 0.46
129215 BRD-K20141153 PC3 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).