CMap Candidate Details

Structure:
CMap ID: C08814
Pert ID: BRD-K20168484
Compound Name: BRD-K20168484
Targets: ALOX5AP
MoA: Lipoxygenase inhibitor
SMILES: CC(C)c1ccc2n(Cc3ccc(Cl)cc3)c(CC(C)(C)C(=O)O)c(SC(C)(C)C)c2c1
InchiKey: QAOAOVKBIIKRNL-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
24417 BRD-K20168484 A375 10 uM 6 h -0.28 -1.18 0.5 0.0 0.0 0.0
24563 BRD-K20168484 A549 10 uM 24 h 0.22 0.93 0.05 -0.31 -1.04 0.67
24756 BRD-K20168484 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24879 BRD-K20168484 HT29 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.1 0.87
25008 BRD-K20168484 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
25146 BRD-K20168484 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
25495 BRD-K20168484 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).