CMap Candidate Details

Structure:
CMap ID: C08825
Pert ID: BRD-K20197062
Compound Name: SA-94315
Targets: CASP3
MoA: Caspase inhibitor
SMILES: COc1ccc(cc1)S(=O)(=O)N(C)C[C@H]2Oc3c(NC(=O)Nc4cccc5ccccc45)cccc3C(=O)N(C[C@@H]2C)[C@@H](C)CO
InchiKey: FXIXTIXYCSOXIT-WDCWYOMISA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
46889 BRD-K20197062 A375 10 uM 6 h 0.29 1.19 0.42 -0.26 -0.86 0.21
47203 BRD-K20197062 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
47557 BRD-K20197062 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
47877 BRD-K20197062 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
48201 BRD-K20197062 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.84 0.18
48529 BRD-K20197062 HT29 10 uM 6 h -0.24 -0.99 0.13 -0.27 -0.89 0.27
49200 BRD-K20197062 PC3 10 uM 24 h -0.18 -0.75 0.0 0.0 0.0 0.0
49630 BRD-K20197062 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
97388 BRD-K20197062 MCF??7.00 0.37 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
97441 BRD-K20197062 NKDBA 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).