CMap Candidate Details

Structure:
CMap ID: C00885
Pert ID: BRD-A36010170
Compound Name: amcinonide
Targets: NR3C1
MoA: Glucocorticoid receptor agonist
SMILES: CC(=O)OCC(=O)[C@@]12OC3(CCCC3)O[C@@H]1CC1C3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]21C
InchiKey: ILKJAFIWWBXGDU-ZYDCGBIBSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5723 BRD-A36010170 HCC515 10 uM 6 h -0.22 -0.9 0.04 -0.29 -0.98 0.49
5836 BRD-A36010170 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.24 -0.82 0.15
6461 BRD-A36010170 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37337 BRD-A36010170 A549 10 uM 6 h 0.0 0.0 0.0 -0.36 -1.22 1.24
37485 BRD-A36010170 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38335 BRD-A36010170 NPC 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.19 1.16
121754 BRD-A36010170 HELA 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121783 BRD-A36010170 HT29 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121816 BRD-A36010170 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.18 0.64 0.0
129747 BRD-A36010170 A375 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129780 BRD-A36010170 HA1E 0.74 uM 24 h 0.24 1.0 0.11 -0.3 -0.99 0.51
129811 BRD-A36010170 HEK293 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129937 BRD-A36010170 MCF10A 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130022 BRD-A36010170 MDAMB231 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130074 BRD-A36010170 PC3 0.25 uM 24 h -0.25 -1.06 0.26 -0.28 -0.94 0.39
130095 BRD-A36010170 THP1 2.22 uM 24 h -0.27 -1.14 0.42 0.0 0.0 0.0
130145 BRD-A36010170 YAPC 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).