CMap Candidate Details

Structure:
CMap ID: C00886
Pert ID: BRD-A36057565
Compound Name: bruceantin
Targets: --
MoA: --
SMILES: COC(=O)[C@]12OC[C@@]34[C@H]1[C@@H](OC(=O)C=C(/C)C(C)C)C(=O)O[C@@H]3C[C@H]1C(C)C(=O)C(=O)C[C@]1(C)[C@H]4[C@@H](O)[C@@H]2O
InchiKey: KMCZIPGKKBSLEX-JLNWNYEJSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
125042 BRD-A36057565 HELA 0.04 uM 24 h 0.26 1.07 0.2 0.0 0.0 0.0
125086 BRD-A36057565 MCF10A 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125186 BRD-A36057565 THP1 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132988 BRD-A36057565 A375 0.01 uM 24 h 0.28 1.17 0.37 -0.39 -1.31 1.71
133003 BRD-A36057565 A549 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133024 BRD-A36057565 HA1E 0.08 uM 24 h 0.28 1.15 0.33 0.0 0.0 0.0
133076 BRD-A36057565 HEK293 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133132 BRD-A36057565 HT29 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133182 BRD-A36057565 JURKAT 0.01 uM 24 h 0.3 1.27 0.58 0.0 0.0 0.0
133244 BRD-A36057565 MCF??7.00 0.01 uM 24 h 0.33 1.39 1.02 0.0 0.0 0.0
133273 BRD-A36057565 MDAMB231 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133303 BRD-A36057565 PC3 0.08 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.93
133327 BRD-A36057565 YAPC 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).