CMap Candidate Details

Structure:
CMap ID: C00891
Pert ID: BRD-A36151937
Compound Name: genistein
Targets: CFTR; ESR2
MoA: Tyrosine kinase inhibitor
SMILES: OCC1OC(Oc2cc(O)c3c(=O)c(coc3c2)c4ccc(O)cc4)C(O)C(O)C1O
InchiKey: ZCOLJUOHXJRHDI-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1492 BRD-A36151937 HA1E 10 uM 24 h 0.23 0.94 0.06 0.0 0.0 0.0
2333 BRD-A36151937 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2646 BRD-A36151937 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.98 0.47
41663 BRD-A36151937 A375 10 uM 6 h -0.22 -0.92 0.06 0.0 0.0 0.0
42008 BRD-A36151937 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42198 BRD-A36151937 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42543 BRD-A36151937 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42849 BRD-A36151937 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43122 BRD-A36151937 MCF??7.00 10 uM 24 h 0.25 1.06 0.19 -0.24 -0.81 0.13
43399 BRD-A36151937 NPC 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.11 0.92
99263 BRD-A36151937 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).