CMap Candidate Details

Structure:
CMap ID: C08962
Pert ID: BRD-K20714604
Compound Name: RS-56812
Targets: HTR3A
MoA: Serotonin receptor partial agonist
SMILES: Cn1cc(C(=O)C(=O)N[C@H]2CN3CCC2CC3)c2ccccc12
InchiKey: ZNAPADWWBWFMCQ-HNNXBMFYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2850 BRD-K20714604 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3161 BRD-K20714604 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3604 BRD-K20714604 PC3 10 uM 6 h 0.0 0.0 0.0 0.27 0.95 0.31
3948 BRD-K20714604 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39102 BRD-K20714604 A375 10 uM 6 h 0.22 0.91 0.03 0.0 0.0 0.0
39308 BRD-K20714604 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39647 BRD-K20714604 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39963 BRD-K20714604 HEPG2 10 uM 6 h 0.22 0.91 0.04 0.27 0.94 0.3
40241 BRD-K20714604 HT29 10 uM 6 h -0.17 -0.69 0.0 -0.32 -1.08 0.79
40598 BRD-K20714604 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.37 1.32 1.59
40770 BRD-K20714604 NEU 10 uM 24 h 0.25 1.04 0.14 0.31 1.09 0.67
41071 BRD-K20714604 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41401 BRD-K20714604 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99737 BRD-K20714604 U2OS 10 uM 6 h 0.25 1.04 0.14 0.26 0.92 0.25
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).