CMap Candidate Details

Structure:
CMap ID: C08965
Pert ID: BRD-K20722021
Compound Name: CEP-32496
Targets: BRAF
MoA: RAF inhibitor
SMILES: COc1cc2ncnc(Oc3cccc(NC(=O)Nc4cc(on4)C(C)(C)C(F)(F)F)c3)c2cc1OC
InchiKey: DKNUPRMJNUQNHR-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
121365 BRD-K20722021 A375 3.33 uM 24 h 0.0 0.0 0.0 0.22 0.79 0.08
121385 BRD-K20722021 HA1E 10 uM 24 h -0.26 -1.07 0.28 0.0 0.0 0.0
121408 BRD-K20722021 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121461 BRD-K20722021 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121479 BRD-K20722021 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121512 BRD-K20722021 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129492 BRD-K20722021 HT29 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).