CMap Candidate Details

Structure:
CMap ID: C08975
Pert ID: BRD-K20738689
Compound Name: dazmegrel
Targets: TBXAS1
MoA: Thromboxane synthase inhibitor
SMILES: Cc1c(Cn2ccnc2)c2ccccc2n1CCC(O)=O
InchiKey: DEQLGSOHGTZKFB-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
121515 BRD-K20738689 YAPC 10 uM 24 h 0.24 1.0 0.1 0.0 0.0 0.0
129407 BRD-K20738689 A375 0.08 uM 24 h 0.0 0.0 0.0 0.3 1.06 0.61
129438 BRD-K20738689 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129466 BRD-K20738689 HELA 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129494 BRD-K20738689 HT29 0.08 uM 24 h 0.0 0.0 0.0 -0.32 -1.08 0.79
129523 BRD-K20738689 MCF??7.00 0.01 uM 24 h -0.22 -0.9 0.04 -0.24 -0.8 0.11
129556 BRD-K20738689 PC3 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).