CMap Candidate Details

Structure:
CMap ID: C08978
Pert ID: BRD-K20742498
Compound Name: RS-39604
Targets: HTR4
MoA: Serotonin receptor antagonist
SMILES: COc1cc(COc2cc(N)c(Cl)cc2C(=O)CCC2CCN(CCNS(C)(=O)=O)CC2)cc(OC)c1
InchiKey: BKVIWGRFRKLFIO-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5308 BRD-K20742498 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5593 BRD-K20742498 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6170 BRD-K20742498 PC3 10 uM 24 h -0.22 -0.9 0.05 0.39 1.38 2.16
6528 BRD-K20742498 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44339 BRD-K20742498 A375 10 uM 6 h 0.27 1.14 0.32 0.0 0.0 0.0
44548 BRD-K20742498 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44897 BRD-K20742498 ASC 10 uM 24 h 0.0 0.0 0.0 -0.19 -0.64 0.01
45199 BRD-K20742498 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45466 BRD-K20742498 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45789 BRD-K20742498 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
46015 BRD-K20742498 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46649 BRD-K20742498 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99738 BRD-K20742498 U2OS 10 uM 6 h 0.0 0.0 0.0 0.27 0.97 0.36
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).