CMap Candidate Details

Structure:
CMap ID: C08979
Pert ID: BRD-K20745393
Compound Name: olprinone
Targets: PDE3A
MoA: Phosphodiesterase inhibitor
SMILES: Cc1[nH]c(=O)c(cc1-c1ccc2nccn2c1)C#N
InchiKey: JPAWFIIYTJQOKW-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
96801 BRD-K20745393 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121366 BRD-K20745393 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121409 BRD-K20745393 HELA 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.84 0.18
121438 BRD-K20745393 HT29 0.125 uM 24 h 0.22 0.93 0.05 0.0 0.0 0.0
121513 BRD-K20745393 YAPC 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129436 BRD-K20745393 HA1E 2.22 uM 24 h 0.14 0.59 0.0 0.0 0.0 0.0
129521 BRD-K20745393 MCF??7.00 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).