CMap Candidate Details

Structure:
CMap ID: C00898
Pert ID: BRD-A36331462
Compound Name: oprozomib
Targets: --
MoA: --
SMILES: COC[C@H](NC(=O)[C@H](COC)NC(=O)c1cnc(C)s1)C(=O)N[C@@H](Cc1ccccc1)C(=O)C1(C)CO1
InchiKey: SWZXEVABPLUDIO-QNLBTCDKSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
95327 BRD-A36331462 A549 1.11 uM 48 h 0.0 0.0 0.0 0.0 0.0 0.0
95441 BRD-A36331462 U2OS 1.11 uM 48 h 0.0 0.0 0.0 0.0 0.0 0.0
120630 BRD-A36331462 HELA 0.125 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.76
120683 BRD-A36331462 HT29 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120737 BRD-A36331462 JURKAT 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120761 BRD-A36331462 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120845 BRD-A36331462 YAPC 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128996 BRD-A36331462 A375 0.08 uM 24 h 0.0 0.0 0.0 0.37 1.3 1.59
129014 BRD-A36331462 HA1E 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129087 BRD-A36331462 PC3 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).