CMap Candidate Details

Structure:
CMap ID: C00901
Pert ID: BRD-A36471396
Compound Name: biperiden
Targets: CHRM1
MoA: Acetylcholine receptor antagonist
SMILES: OC(CCN1CCCCC1)(C2C[C@H]3C[C@@H]2C=C3)c4ccccc4
InchiKey: YSXKPIUOCJLQIE-BDWAOYLISA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4167 BRD-A36471396 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.94 0.37
4300 BRD-A36471396 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4749 BRD-A36471396 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4850 BRD-A36471396 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.16 1.11
37068 BRD-A36471396 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37338 BRD-A36471396 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37488 BRD-A36471396 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37811 BRD-A36471396 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.86 0.2
38006 BRD-A36471396 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38150 BRD-A36471396 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.33 1.17 0.92
38338 BRD-A36471396 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38630 BRD-A36471396 PHH 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.78 0.09
38852 BRD-A36471396 SKB 10 uM 24 h 0.23 0.98 0.09 -0.22 -0.73 0.05
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).