CMap Candidate Details

Structure:
CMap ID: C09031
Pert ID: BRD-K20897876
Compound Name: castanospermine
Targets: GAA; GBA
MoA: Glucosidase inhibitor
SMILES: O[C@H]1CCN2C[C@H](O)[C@@H](O)[C@H](O)[C@@H]12
InchiKey: JDVVGAQPNNXQDW-TVNFTVLESA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
121367 BRD-K20897876 A375 0.04 uM 24 h 0.0 0.0 0.0 0.25 0.88 0.19
121386 BRD-K20897876 HA1E 0.04 uM 24 h -0.2 -0.81 0.0 0.29 1.04 0.56
121411 BRD-K20897876 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121516 BRD-K20897876 YAPC 0.125 uM 24 h 0.32 1.35 0.94 0.0 0.0 0.0
129495 BRD-K20897876 HT29 0.08 uM 24 h 0.35 1.46 1.12 0.27 0.97 0.35
129524 BRD-K20897876 MCF??7.00 0.01 uM 24 h 0.0 0.0 0.0 0.2 0.71 0.02
129557 BRD-K20897876 PC3 0.25 uM 24 h -0.25 -1.04 0.21 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).