CMap Candidate Details

Structure:
CMap ID: C00908
Pert ID: BRD-A37052580
Compound Name: physostigmine
Targets: ACHE
MoA: Cholinesterase inhibitor; Acetylcholinesterase inhibitor
SMILES: CNC(=O)Oc1ccc2N(C)C3N(C)CC[C@@]3(C)c2c1
InchiKey: PIJVFDBKTWXHHD-WUJWULDRSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
24379 BRD-A37052580 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24525 BRD-A37052580 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
24718 BRD-A37052580 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24840 BRD-A37052580 HT29 10 uM 6 h 0.0 0.0 0.0 0.22 0.78 0.06
25066 BRD-A37052580 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25216 BRD-A37052580 PC3 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.89 0.27
25288 BRD-A37052580 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96061 BRD-A37052580 PHH 10 uM 24 h 0.0 0.0 0.0 0.35 1.23 1.19
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).