CMap Candidate Details

Structure:
CMap ID: C09135
Pert ID: BRD-K21283037
Compound Name: riluzole
Targets: SCN5A
MoA: Glutamate inhibitor
SMILES: Nc1nc2ccc(OC(F)(F)F)cc2s1
InchiKey: FTALBRSUTCGOEG-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1461 BRD-K21283037 NPC 4 uM 24 h 0.0 0.0 0.0 -0.29 -0.98 0.5
3344 BRD-K21283037 HCC515 10 uM 6 h -0.23 -0.98 0.12 -0.36 -1.2 1.21
3749 BRD-K21283037 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
24564 BRD-K21283037 A549 10 uM 24 h 0.0 0.0 0.0 0.32 1.13 0.84
39648 BRD-K21283037 ASC 10 uM 24 h 0.0 0.0 0.0 0.24 0.85 0.15
39964 BRD-K21283037 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.38 -1.28 1.45
41402 BRD-K21283037 SKB 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.81 0.14
91174 BRD-K21283037 HUH7 15 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
98355 BRD-K21283037 NEU 10 uM 24 h 0.23 0.97 0.08 0.0 0.0 0.0
99741 BRD-K21283037 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
121369 BRD-K21283037 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121387 BRD-K21283037 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.83 0.16
121413 BRD-K21283037 HELA 10 uM 24 h 0.24 0.99 0.1 -0.39 -1.33 1.71
121440 BRD-K21283037 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121463 BRD-K21283037 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121481 BRD-K21283037 PC3 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.1 0.87
121518 BRD-K21283037 YAPC 0.37 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.39
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).