CMap Candidate Details

Structure:
CMap ID: C09139
Pert ID: BRD-K21295289
Compound Name: senicapoc
Targets: KCNN4
MoA: Intermediate conductance potassium channel blocker
SMILES: NC(=O)C(c1ccccc1)(c1ccc(F)cc1)c1ccc(F)cc1
InchiKey: SCTZUZTYRMOMKT-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
120907 BRD-K21295289 HA1E 0.125 uM 24 h 0.0 0.0 0.0 -0.25 -0.85 0.2
120945 BRD-K21295289 HEK293 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121014 BRD-K21295289 HT29 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121037 BRD-K21295289 MCF??7.00 0.04 uM 24 h 0.19 0.79 0.0 0.0 0.0 0.0
121072 BRD-K21295289 PC3 1.11 uM 24 h 0.0 0.0 0.0 -0.29 -0.96 0.44
121103 BRD-K21295289 YAPC 0.37 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.54
129095 BRD-K21295289 A375 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129112 BRD-K21295289 A549 2.22 uM 24 h 0.25 1.06 0.18 -0.2 -0.69 0.02
129161 BRD-K21295289 HELA 2.22 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).