CMap Candidate Details

Structure:
CMap ID: C09147
Pert ID: BRD-K21317336
Compound Name: phentolamine
Targets: ADRA1A; ADRA2A
MoA: Adrenergic receptor antagonist
SMILES: Cc1ccc(cc1)N(CC1=NCCN1)c1ccc(O)cc1
InchiKey: LBXLJKWLYGGOTD-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
49824 BRD-K21317336 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
49993 BRD-K21317336 A549 10 uM 6 h 0.0 0.0 0.0 0.36 1.27 1.34
50168 BRD-K21317336 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50518 BRD-K21317336 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50661 BRD-K21317336 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
50919 BRD-K21317336 PC3 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.87 0.24
51019 BRD-K21317336 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).