CMap Candidate Details

Structure:
CMap ID: C00915
Pert ID: BRD-A37432947
Compound Name: ipratropium
Targets: CHRM1; CHRM2; CHRM3; CHRM4
MoA: Acetylcholine receptor antagonist
SMILES: CC(C)[N+]1(C)[C@@H]2CC[C@@H]1C[C@H](C2)OC(=O)C(CO)c3ccccc3
InchiKey: OEXHQOGQTVQTAT-ZFWRPDKHSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6834 BRD-A37432947 A375 10 uM 6 h -0.24 -0.98 0.12 0.0 0.0 0.0
7067 BRD-A37432947 A549 10 uM 6 h 0.0 0.0 0.0 -0.38 -1.27 1.44
7219 BRD-A37432947 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7526 BRD-A37432947 HCC515 10 uM 6 h -0.26 -1.07 0.26 -0.28 -0.94 0.36
7942 BRD-A37432947 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8122 BRD-A37432947 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8436 BRD-A37432947 PC3 10 uM 6 h 0.0 0.0 0.0 0.33 1.16 0.91
8752 BRD-A37432947 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).