CMap Candidate Details

Structure:
CMap ID: C09154
Pert ID: BRD-K21350491
Compound Name: phenamil
Targets: PKD2L1
MoA: TRPV antagonist
SMILES: Nc1nc(N)c(nc1Cl)C(=O)NC(=N)Nc2ccccc2
InchiKey: NIOHELZQFBGCEO-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6871 BRD-K21350491 A375 10 uM 6 h 0.0 0.0 0.0 0.29 1.04 0.56
7145 BRD-K21350491 A549 10 uM 6 h 0.0 0.0 0.0 -0.35 -1.19 1.15
7303 BRD-K21350491 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.19 1.15
7636 BRD-K21350491 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.94 0.39
7847 BRD-K21350491 HT29 10 uM 24 h 0.2 0.82 0.0 0.0 0.0 0.0
8234 BRD-K21350491 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8355 BRD-K21350491 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8655 BRD-K21350491 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90988 BRD-K21350491 HUH7 10 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
99742 BRD-K21350491 U2OS 15 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).