CMap Candidate Details

Structure:
CMap ID: C09157
Pert ID: BRD-K21361524
Compound Name: KPT-330
Targets: --
MoA: --
SMILES: FC(F)(F)c1cc(cc(c1)C(F)(F)F)-c1ncn(C=C/C(=O)NNc2cnccn2)n1
InchiKey: DEVSOMFAQLZNKR-RJRFIUFISA-N
Compound Aliases: selinexor

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
120858 BRD-K21361524 A375 0.37 uM 24 h 0.0 0.0 0.0 -0.39 -1.31 1.71
120904 BRD-K21361524 HA1E 0.37 uM 24 h 0.0 0.0 0.0 -0.39 -1.32 1.71
120941 BRD-K21361524 HEK293 3.33 uM 24 h -0.31 -1.3 0.81 -0.27 -0.91 0.31
120998 BRD-K21361524 HELA 1.11 uM 3 h -0.27 -1.13 0.4 -0.39 -1.32 1.71
121033 BRD-K21361524 MCF??7.00 1.11 uM 24 h 0.0 0.0 0.0 -0.31 -1.03 0.63
121099 BRD-K21361524 YAPC 1.11 uM 24 h 0.18 0.77 0.0 0.0 0.0 0.0
129109 BRD-K21361524 A549 0.25 uM 24 h -0.3 -1.25 0.69 0.0 0.0 0.0
129185 BRD-K21361524 HT29 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129216 BRD-K21361524 PC3 2.22 uM 24 h 0.0 0.0 0.0 -0.4 -1.35 2.01
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).