CMap Candidate Details

Structure:
CMap ID: C00921
Pert ID: BRD-A37541666
Compound Name: naloxone
Targets: OPRD1; OPRK1; OPRM1
MoA: Opioid receptor antagonist
SMILES: Oc1ccc2CC3N(CC=C)CCC4(C5Oc1c24)C3(O)CCC5=O
InchiKey: UZHSEJADLWPNLE-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6835 BRD-A37541666 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7069 BRD-A37541666 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7221 BRD-A37541666 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7762 BRD-A37541666 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8264 BRD-A37541666 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8437 BRD-A37541666 PC3 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.86 0.2
8569 BRD-A37541666 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.19 1.15
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).