CMap Candidate Details

Structure:
CMap ID: C00922
Pert ID: BRD-A37630846
Compound Name: daunorubicin
Targets: TOP2A
MoA: RNA synthesis inhibitor; Topoisomerase inhibitor
SMILES: COc1cccc2C(=O)c3c(O)c4CC(O)(CC(OC5CC(N)C(O)C(C)O5)c4c(O)c3C(=O)c12)C(=O)C
InchiKey: STQGQHZAVUOBTE-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1193 BRD-A37630846 PC3 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
1266 BRD-A37630846 A549 1.11 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
1277 BRD-A37630846 MCF??7.00 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
1408 BRD-A37630846 U2OS 0.12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
90700 BRD-A37630846 HA1E 1.11 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
90709 BRD-A37630846 U937 1.11 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).