CMap Candidate Details

Structure:
CMap ID: C09225
Pert ID: BRD-K21547160
Compound Name: sufentanil
Targets: OPRM1
MoA: Opiod receptor modulator
SMILES: CCC(=O)N(c1ccccc1)C1(COC)CCN(CCc2cccs2)CC1
InchiKey: GGCSSNBKKAUURC-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
121370 BRD-K21547160 A375 0.37 uM 24 h 0.18 0.76 0.0 0.33 1.15 0.9
121441 BRD-K21547160 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121464 BRD-K21547160 MCF??7.00 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121482 BRD-K21547160 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121519 BRD-K21547160 YAPC 10 uM 24 h 0.26 1.1 0.24 0.0 0.0 0.0
129440 BRD-K21547160 HA1E 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129467 BRD-K21547160 HELA 0.25 uM 24 h -0.25 -1.03 0.2 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).