CMap Candidate Details

Structure:
CMap ID: C09266
Pert ID: BRD-K21667562
Compound Name: AM-404
Targets: TRPV1
MoA: FAAH inhibitor; TRPV antagonist; Cyclooxygenase inhibitor
SMILES: CCCCCC=CCC=CCC=CCC=CCCCC(=O)Nc1ccc(O)cc1
InchiKey: IJBZOOZRAXHERC-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1563 BRD-K21667562 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
1901 BRD-K21667562 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2169 BRD-K21667562 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2654 BRD-K21667562 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41743 BRD-K21667562 A375 10 uM 6 h 0.0 0.0 0.0 -0.24 -0.8 0.11
42078 BRD-K21667562 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42324 BRD-K21667562 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42653 BRD-K21667562 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42957 BRD-K21667562 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43305 BRD-K21667562 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43515 BRD-K21667562 NPC 10 uM 24 h 0.25 1.05 0.17 -0.4 -1.36 2.02
43813 BRD-K21667562 PHH 10 uM 24 h 0.32 1.34 0.89 0.0 0.0 0.0
44089 BRD-K21667562 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99747 BRD-K21667562 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).