CMap Candidate Details

Structure:
CMap ID: C00927
Pert ID: BRD-A37776212
Compound Name: ICI-204448
Targets: OPRK1
MoA: Opioid receptor agonist
SMILES: CN(C(CN1CCCC1)c2cccc(OCC(=O)O)c2)C(=O)Cc3ccc(Cl)c(Cl)c3
InchiKey: JKYJSFISYHSNOE-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6836 BRD-A37776212 A375 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.11 0.92
6926 BRD-A37776212 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7222 BRD-A37776212 HA1E 10 uM 24 h 0.24 1.01 0.12 0.0 0.0 0.0
7528 BRD-A37776212 HCC515 10 uM 6 h 0.23 0.97 0.08 -0.35 -1.18 1.14
7943 BRD-A37776212 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8241 BRD-A37776212 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.1 0.86
8438 BRD-A37776212 PC3 10 uM 6 h 0.21 0.86 0.01 -0.38 -1.28 1.45
8570 BRD-A37776212 VCAP 10 uM 24 h 0.0 0.0 0.0 0.26 0.93 0.26
136428 BRD-A37776212 SHSY5Y 0.04 uM 24 h 0.0 0.0 0.0 -0.34 -1.15 1.07
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).