CMap Candidate Details

Structure:
CMap ID: C09270
Pert ID: BRD-K21672174
Compound Name: Ro-28-1675
Targets: GCK
MoA: Glucokinase activator
SMILES: CS(=O)(=O)c1ccc(cc1)[C@@H](CC1CCCC1)C(=O)Nc1nccs1
InchiKey: NEQSWPCDHDQINX-MRXNPFEDSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8925 BRD-K21672174 A375 150 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9385 BRD-K21672174 AGS 150 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9698 BRD-K21672174 H1299 150 uM 6 h 0.0 0.0 0.0 -0.31 -1.06 0.73
10046 BRD-K21672174 HA1E 150 uM 6 h 0.0 0.0 0.0 -0.27 -0.9 0.29
10266 BRD-K21672174 HCC515 150 uM 6 h -0.2 -0.85 0.01 -0.37 -1.23 1.28
10482 BRD-K21672174 HCT116 150 uM 6 h 0.0 0.0 0.0 -0.27 -0.9 0.29
10758 BRD-K21672174 HEPG2 150 uM 6 h -0.19 -0.79 0.0 -0.6 -2.02 15.65
11064 BRD-K21672174 HT29 150 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11275 BRD-K21672174 MCF??7.00 150 uM 6 h 0.0 0.0 0.0 -0.29 -0.98 0.49
11447 BRD-K21672174 NCIH2073 150 uM 6 h -0.19 -0.81 0.0 -0.45 -1.5 15.35
11736 BRD-K21672174 NCIH508 150 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12012 BRD-K21672174 NCIH596 150 uM 6 h -0.19 -0.78 0.0 -0.41 -1.39 2.02
12288 BRD-K21672174 NOMO1 150 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12598 BRD-K21672174 PC3 150 uM 6 h 0.2 0.85 0.01 -0.46 -1.55 15.65
12759 BRD-K21672174 SW480 150 uM 6 h 0.0 0.0 0.0 -0.23 -0.79 0.1
12955 BRD-K21672174 THP1 150 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13239 BRD-K21672174 U937 150 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13601 BRD-K21672174 VCAP 150 uM 6 h 0.0 0.0 0.0 -0.43 -1.43 15.35
90571 BRD-K21672174 A549 1.11 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).