CMap Candidate Details

Structure:
CMap ID: C00928
Pert ID: BRD-A37780065
Compound Name: triamcinolone
Targets: NR3C1
MoA: Glucocorticoid receptor agonist
SMILES: C[C@]12C[C@H](O)[C@@]3(F)C(CCC4=CC(=O)C=C[C@]34C)C1C[C@@H](O)[C@]2(O)C(=O)CO
InchiKey: GFNANZIMVAIWHM-MGVPRKGPSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
7529 BRD-A37780065 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8571 BRD-A37780065 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123259 BRD-A37780065 A549 3.33 uM 24 h -0.26 -1.1 0.34 0.0 0.0 0.0
123412 BRD-A37780065 PC3 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131522 BRD-A37780065 A375 0.74 uM 24 h -0.21 -0.87 0.02 0.0 0.0 0.0
131574 BRD-A37780065 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131612 BRD-A37780065 HEK293 0.01 uM 24 h 0.0 0.0 0.0 -0.32 -1.09 0.84
131649 BRD-A37780065 HELA 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131676 BRD-A37780065 HT29 2.22 uM 24 h 0.0 0.0 0.0 0.21 0.75 0.04
131705 BRD-A37780065 HUVEC 0.08 uM 24 h 0.0 0.0 0.0 -0.23 -0.78 0.09
131758 BRD-A37780065 JURKAT 0.74 uM 24 h 0.0 0.0 0.0 -0.29 -0.99 0.51
131812 BRD-A37780065 MCF10A 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131842 BRD-A37780065 MCF??7.00 0.08 uM 24 h 0.0 0.0 0.0 0.35 1.23 1.19
131880 BRD-A37780065 MDAMB231 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131925 BRD-A37780065 THP1 2.22 uM 24 h 0.0 0.0 0.0 -0.33 -1.11 0.92
131946 BRD-A37780065 YAPC 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).