CMap Candidate Details

Structure:
CMap ID: C09311
Pert ID: BRD-K21806131
Compound Name: tegaserod
Targets: HTR2B; HTR4
MoA: Serotonin receptor partial agonist
SMILES: CCCCCN=C(/N)NN=Cc1c[nH]c2ccc(OC)cc12
InchiKey: IKBKZGMPCYNSLU-RGVLZGJSSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
24418 BRD-K21806131 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24565 BRD-K21806131 A549 10 uM 24 h 0.0 0.0 0.0 -0.43 -1.45 15.35
24881 BRD-K21806131 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25010 BRD-K21806131 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
25240 BRD-K21806131 PC3 10 uM 6 h -0.22 -0.93 0.07 0.0 0.0 0.0
25340 BRD-K21806131 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).