CMap Candidate Details

Structure:
CMap ID: C09321
Pert ID: BRD-K21853356
Compound Name: RG-14620
Targets: EGFR
MoA: EGFR inhibitor
SMILES: Clc1cc(Cl)cc(/C=C(C#N)/c2cccnc2)c1
InchiKey: TYXIVBJQPBWBHO-UUILKARUSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4204 BRD-K21853356 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4392 BRD-K21853356 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4664 BRD-K21853356 PC3 10 uM 24 h -0.23 -0.94 0.08 0.3 1.06 0.6
4909 BRD-K21853356 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37275 BRD-K21853356 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37615 BRD-K21853356 ASC 10 uM 24 h 0.3 1.26 0.56 0.0 0.0 0.0
38064 BRD-K21853356 HT29 10 uM 6 h 0.0 0.0 0.0 0.35 1.22 1.16
38189 BRD-K21853356 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.25 0.88 0.18
38445 BRD-K21853356 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38925 BRD-K21853356 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99749 BRD-K21853356 U2OS 20 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).