CMap Candidate Details

Structure:
CMap ID: C09328
Pert ID: BRD-K21884483
Compound Name: mizolastine
Targets: HRH1
MoA: Histamine receptor antagonist
SMILES: CN(C1CCN(CC1)c1nc2ccccc2n1Cc1ccc(F)cc1)c1nccc(=O)[nH]1
InchiKey: PVLJETXTTWAYEW-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
121372 BRD-K21884483 A375 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121443 BRD-K21884483 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121525 BRD-K21884483 YAPC 0.04 uM 24 h 0.3 1.24 0.53 -0.29 -0.99 0.5
129443 BRD-K21884483 HA1E 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129469 BRD-K21884483 HELA 0.08 uM 24 h 0.27 1.11 0.26 0.0 0.0 0.0
129526 BRD-K21884483 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.33
129561 BRD-K21884483 PC3 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).