CMap Candidate Details

Structure:
CMap ID: C09343
Pert ID: BRD-K21936341
Compound Name: oxotremorine-sesquifumarate
Targets: CHRM2
MoA: Cholinergic receptor agonist
SMILES: O=C1CCCN1CC#CCN1CCCC1
InchiKey: RSDOPYMFZBJHRL-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6732 BRD-K21936341 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6981 BRD-K21936341 A549 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.9 0.29
7431 BRD-K21936341 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.12 0.96
7848 BRD-K21936341 HT29 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.93 0.35
8171 BRD-K21936341 MCF??7.00 10 uM 6 h 0.27 1.12 0.26 -0.28 -0.95 0.41
8497 BRD-K21936341 PC3 10 uM 6 h 0.0 0.0 0.0 -0.4 -1.33 1.8
8807 BRD-K21936341 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.88 0.26
91002 BRD-K21936341 HUH7 15 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).