CMap Candidate Details

Structure:
CMap ID: C00938
Pert ID: BRD-A38076815
Compound Name: glafenine
Targets: CFTR
MoA: DeltaF508-CFTR Corrector
SMILES: OCC(O)COC(=O)c1ccccc1Nc1ccnc2cc(Cl)ccc12
InchiKey: GWOFUCIGLDBNKM-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
121553 BRD-A38076815 A375 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121590 BRD-A38076815 HA1E 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121631 BRD-A38076815 HELA 0.37 uM 24 h 0.24 0.98 0.09 -0.34 -1.16 1.11
129627 BRD-A38076815 HT29 0.74 uM 24 h 0.0 0.0 0.0 0.29 1.02 0.49
129657 BRD-A38076815 MCF??7.00 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129681 BRD-A38076815 PC3 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129720 BRD-A38076815 YAPC 0.08 uM 24 h 0.0 0.0 0.0 -0.29 -0.98 0.47
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).