CMap Candidate Details

Structure:
CMap ID: C09396
Pert ID: BRD-K22096725
Compound Name: ALW-II-49-7
Targets: DDR1
MoA: Ephrin inhibitor
SMILES: Cc1ccc(cc1Nc1cncc(c1)C(N)=O)C(=O)Nc1cccc(c1)C(F)(F)F
InchiKey: SAAYRHKJHDIDPH-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
30992 BRD-K22096725 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
31681 BRD-K22096725 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
32151 BRD-K22096725 NEU 10 uM 24 h 0.0 0.0 0.0 -0.39 -1.31 1.71
32975 BRD-K22096725 SKB 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.25 1.35
33443 BRD-K22096725 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
91505 BRD-K22096725 BT20 10 uM 24 h -0.23 -0.96 0.09 0.0 0.0 0.0
91600 BRD-K22096725 HS578T 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
91645 BRD-K22096725 MCF??7.00 10 uM 24 h -0.19 -0.81 0.0 0.0 0.0 0.0
91725 BRD-K22096725 SKBR3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92860 BRD-K22096725 A375 0.12 uM 24 h -0.28 -1.17 0.48 0.0 0.0 0.0
92887 BRD-K22096725 A549 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.09 0.84
92915 BRD-K22096725 ASC 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.72
92972 BRD-K22096725 CD34 0.04 uM 24 h 0.0 0.0 0.0 0.33 1.16 0.9
93029 BRD-K22096725 HA1E 1.11 uM 24 h 0.0 0.0 0.0 0.31 1.11 0.74
93065 BRD-K22096725 HEK293 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.86 0.2
93113 BRD-K22096725 HELA 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93152 BRD-K22096725 HEPG2 3.33 uM 24 h 0.0 0.0 0.0 -0.3 -1.02 0.59
93199 BRD-K22096725 HUVEC 10 uM 24 h 0.0 0.0 0.0 -0.47 -1.58 15.65
93255 BRD-K22096725 JURKAT 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93302 BRD-K22096725 MCF10A 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.17 1.14
93342 BRD-K22096725 MDAMB231 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.67
93383 BRD-K22096725 NPC 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.81 0.13
93436 BRD-K22096725 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93469 BRD-K22096725 SKL 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93528 BRD-K22096725 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93569 BRD-K22096725 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).