CMap Candidate Details
Structure:
| CMap ID: | C09403 |
| Pert ID: | BRD-K22127577 |
| Compound Name: | crenolanib |
| Targets: | PDGFRA; PDGFRB |
| MoA: | PDGFR inhibitor |
| SMILES: | CC1(COc2ccc3n(cnc3c2)-c2ccc3cccc(N4CCC(N)CC4)c3n2)COC1 |
| InchiKey: | DYNHJHQFHQTFTP-UHFFFAOYSA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 96608 | BRD-K22127577 | A375 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.22 | 0.79 | 0.07 |
| 96681 | BRD-K22127577 | PC3 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.31 | -1.05 | 0.71 |