CMap Candidate Details
Structure:
| CMap ID: | C09413 |
| Pert ID: | BRD-K22149900 |
| Compound Name: | ceritinib |
| Targets: | ALK |
| MoA: | ALK inhibitor |
| SMILES: | CC(C)Oc1cc(C2CCNCC2)c(C)cc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 |
| InchiKey: | VERWOWGGCGHDQE-UHFFFAOYSA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 1267 | BRD-K22149900 | A549 | 1.11 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 1278 | BRD-K22149900 | MCF??7.00 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 1340 | BRD-K22149900 | U2OS | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.37 | -1.23 | 1.28 |
| 96487 | BRD-K22149900 | A375 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 96554 | BRD-K22149900 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |