CMap Candidate Details
Structure:
| CMap ID: | C00943 |
| Pert ID: | BRD-A38350138 |
| Compound Name: | ketoconazole |
| Targets: | CYP19A1; AR |
| MoA: | Sterol demethylase inhibitor |
| SMILES: | CC(=O)N1CCN(CC1)c1ccc(OCC2CO[C@@](Cn3ccnc3)(O2)c2ccc(Cl)cc2Cl)cc1 |
| InchiKey: | XMAYWYJOQHXEEK-NASUQTAISA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 123523 | BRD-A38350138 | A375 | 10 uM | 24 h | -0.24 | -1.02 | 0.17 | 0.0 | 0.0 | 0.0 |
| 123545 | BRD-A38350138 | HA1E | 10 uM | 24 h | -0.19 | -0.8 | 0.0 | 0.31 | 1.09 | 0.67 |
| 123590 | BRD-A38350138 | HEK293 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.23 | -0.79 | 0.1 |
| 123626 | BRD-A38350138 | HELA | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.32 | 1.12 | 0.76 |
| 123660 | BRD-A38350138 | HT29 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 123705 | BRD-A38350138 | MCF10A | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 123731 | BRD-A38350138 | MCF??7.00 | 10 uM | 24 h | 0.22 | 0.92 | 0.04 | 0.0 | 0.0 | 0.0 |
| 123746 | BRD-A38350138 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 123774 | BRD-A38350138 | YAPC | 10 uM | 24 h | -0.25 | -1.03 | 0.19 | 0.0 | 0.0 | 0.0 |