CMap Candidate Details

Structure:
CMap ID: C00954
Pert ID: BRD-A38898897
Compound Name: GW-311616
Targets: ELANE
MoA: Leukocyte elastase inhibitor
SMILES: CC(C)C1[C@H]2[C@@H](CCN2C(=O)/C=C/CN3CCCCC3)N(C1=O)S(=O)(=O)C
InchiKey: NDNKNUMSTIMSHQ-PTJVQUAFSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1495 BRD-A38898897 HA1E 10 uM 24 h 0.0 0.0 0.0 0.2 0.7 0.01
2037 BRD-A38898897 HCC515 10 uM 6 h 0.0 0.0 0.0 0.35 1.23 1.19
2334 BRD-A38898897 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2566 BRD-A38898897 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41664 BRD-A38898897 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42011 BRD-A38898897 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42201 BRD-A38898897 ASC 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.02 0.6
42546 BRD-A38898897 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.36 -1.2 1.17
42852 BRD-A38898897 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43259 BRD-A38898897 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.27 0.96 0.34
43402 BRD-A38898897 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).