CMap Candidate Details

Structure:
CMap ID: C00955
Pert ID: BRD-A38913120
Compound Name: BH3I-1
Targets: BCL2L1
MoA: BCL inhibitor
SMILES: CC(C)C(N1C(=O)/C(=C/c2ccc(Br)cc2)/SC1=S)C(=O)O
InchiKey: COHIEJLWRGREHV-XFFZJAGNSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1689 BRD-A38913120 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
1822 BRD-A38913120 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.96 0.42
2335 BRD-A38913120 PC3 10 uM 6 h 0.19 0.78 0.0 -0.23 -0.79 0.1
2709 BRD-A38913120 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41665 BRD-A38913120 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41879 BRD-A38913120 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42202 BRD-A38913120 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42547 BRD-A38913120 HEPG2 10 uM 6 h -0.29 -1.19 0.55 0.0 0.0 0.0
42853 BRD-A38913120 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43124 BRD-A38913120 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.28 1.0 0.42
43403 BRD-A38913120 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43716 BRD-A38913120 PHH 10 uM 24 h 0.0 0.0 0.0 0.35 1.24 1.28
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).