CMap Candidate Details

Structure:
CMap ID: C00959
Pert ID: BRD-A39052811
Compound Name: mosapride
Targets: HTR4
MoA: Serotonin receptor agonist
SMILES: CCOc1cc(N)c(Cl)cc1C(=O)NCC1CN(Cc2ccc(F)cc2)CCO1
InchiKey: YPELFRMCRYSPKZ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
24380 BRD-A39052811 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24526 BRD-A39052811 A549 10 uM 24 h 0.0 0.0 0.0 0.25 0.87 0.18
24719 BRD-A39052811 HA1E 10 uM 6 h 0.0 0.0 0.0 0.23 0.81 0.09
24986 BRD-A39052811 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
25128 BRD-A39052811 PC3 10 uM 24 h -0.28 -1.15 0.43 0.0 0.0 0.0
25472 BRD-A39052811 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.35 -1.18 1.14
33989 BRD-A39052811 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
34503 BRD-A39052811 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34774 BRD-A39052811 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35048 BRD-A39052811 HT29 10 uM 6 h 0.21 0.86 0.01 0.3 1.08 0.65
35511 BRD-A39052811 NEU 10 uM 24 h -0.27 -1.14 0.42 0.0 0.0 0.0
35683 BRD-A39052811 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36147 BRD-A39052811 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36441 BRD-A39052811 SKB 10 uM 24 h 0.0 0.0 0.0 0.3 1.05 0.57
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).