CMap Candidate Details

Structure:
CMap ID: C09600
Pert ID: BRD-K22749967
Compound Name: ABT-239
Targets: HRH3
MoA: Histamine receptor antagonist
SMILES: C[C@@H]1CCCN1CCc1cc2cc(ccc2o1)-c1ccc(cc1)C#N
InchiKey: KFHYZKCRXNRKRC-MRXNPFEDSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
120864 BRD-K22749967 A375 10 uM 24 h 0.0 0.0 0.0 0.39 1.36 1.76
120887 BRD-K22749967 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120910 BRD-K22749967 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120954 BRD-K22749967 HEK293 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121018 BRD-K22749967 HT29 10 uM 24 h -0.21 -0.87 0.02 0.0 0.0 0.0
121042 BRD-K22749967 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.2 0.71 0.02
121076 BRD-K22749967 PC3 10 uM 24 h 0.0 0.0 0.0 0.31 1.09 0.67
121110 BRD-K22749967 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129163 BRD-K22749967 HELA 2.22 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).