CMap Candidate Details

Structure:
CMap ID: C09629
Pert ID: BRD-K22848513
Compound Name: BRD-K22848513
Targets: --
MoA: --
SMILES: COC(=O)[C@]12CCC(C)(C)C[C@@H]1[C@@H]1C(=O)C=C3[C@]4(C)C=C(C#N)C(=O)C(C)(C)[C@@H]4CC[C@@]3(C)[C@]1(C)CC2
InchiKey: WPTTVJLTNAWYAO-RRPQCQSHSA-N
Compound Aliases: bardoxolone-methyl

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
120863 BRD-K22848513 A375 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120909 BRD-K22848513 HA1E 0.37 uM 24 h 0.27 1.15 0.32 0.29 1.01 0.46
120952 BRD-K22848513 HEK293 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121040 BRD-K22848513 MCF??7.00 0.37 uM 24 h 0.0 0.0 0.0 0.35 1.22 1.19
121074 BRD-K22848513 PC3 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121108 BRD-K22848513 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129114 BRD-K22848513 A549 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129162 BRD-K22848513 HELA 0.08 uM 3 h -0.18 -0.75 0.0 0.0 0.0 0.0
129188 BRD-K22848513 HT29 0.25 uM 24 h 0.23 0.98 0.09 0.29 1.01 0.46
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).