CMap Candidate Details

Structure:
CMap ID: C00969
Pert ID: BRD-A39290993
Compound Name: cyproterone
Targets: AR
MoA: Androgen receptor antagonist
SMILES: CC(=O)O[C@@]1(CC[C@H]2[C@@H]3C=C(Cl)C4=CC(=O)C5CC5[C@]4(C)[C@H]3CC[C@@]21C)C(=O)C
InchiKey: UWFYSQMTEOIJJG-NKGGGRBPSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4016 BRD-A39290993 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.77 0.08
4302 BRD-A39290993 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4617 BRD-A39290993 PC3 10 uM 24 h -0.26 -1.1 0.34 -0.27 -0.9 0.29
4994 BRD-A39290993 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37070 BRD-A39290993 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37232 BRD-A39290993 A549 10 uM 24 h -0.24 -0.99 0.13 0.0 0.0 0.0
37490 BRD-A39290993 ASC 10 uM 24 h -0.24 -1.0 0.14 -0.33 -1.12 0.96
37813 BRD-A39290993 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38008 BRD-A39290993 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38250 BRD-A39290993 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38340 BRD-A39290993 NPC 10 uM 24 h 0.32 1.32 0.82 -0.33 -1.11 0.9
38632 BRD-A39290993 PHH 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.74 0.05
38853 BRD-A39290993 SKB 10 uM 24 h -0.26 -1.09 0.33 -0.16 -0.55 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).