CMap Candidate Details

Structure:
CMap ID: C09895
Pert ID: BRD-K23728141
Compound Name: tafamidis-meglumine
Targets: TTR
MoA: Transthyretin stabilizer; Transthyretin amyloid inhibitor
SMILES: OC(=O)c1ccc2nc(oc2c1)-c1cc(Cl)cc(Cl)c1
InchiKey: TXEIIPDJKFWEEC-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
120866 BRD-K23728141 A375 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120888 BRD-K23728141 A549 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120956 BRD-K23728141 HEK293 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121044 BRD-K23728141 MCF??7.00 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121078 BRD-K23728141 PC3 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121112 BRD-K23728141 YAPC 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129136 BRD-K23728141 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.22 0.77 0.06
129164 BRD-K23728141 HELA 0.08 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
129191 BRD-K23728141 HT29 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).