CMap Candidate Details

Structure:
CMap ID: C09939
Pert ID: BRD-K23875128
Compound Name: BRD-K23875128
Targets: --
MoA: --
SMILES: c1[nH]c2ccccc2c1c3ccncc3
InchiKey: LLJRXVHJOJRCSM-UHFFFAOYSA-N
Compound Aliases: RHO-kinase-inhibitor-III[rockout]

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9093 BRD-K23875128 A549 10 uM 24 h -0.24 -1.0 0.14 -0.34 -1.14 1.05
9388 BRD-K23875128 AGS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9700 BRD-K23875128 H1299 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10047 BRD-K23875128 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10352 BRD-K23875128 HCC515 10 uM 6 h -0.27 -1.12 0.38 -0.27 -0.92 0.34
10484 BRD-K23875128 HCT116 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10760 BRD-K23875128 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10963 BRD-K23875128 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11450 BRD-K23875128 NCIH2073 10 uM 6 h 0.0 0.0 0.0 -0.39 -1.32 1.71
12015 BRD-K23875128 NCIH596 10 uM 6 h -0.29 -1.19 0.53 -0.3 -1.02 0.61
12291 BRD-K23875128 NOMO1 10 uM 6 h 0.0 0.0 0.0 -0.42 -1.41 2.02
12599 BRD-K23875128 PC3 10 uM 6 h -0.2 -0.85 0.01 0.0 0.0 0.0
12762 BRD-K23875128 SW480 10 uM 6 h 0.28 1.18 0.39 0.23 0.81 0.09
13242 BRD-K23875128 U937 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13603 BRD-K23875128 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
96054 BRD-K23875128 PHH 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98799 BRD-K23875128 NPC 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
99014 BRD-K23875128 NEU 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
124283 BRD-K23875128 A375 10 uM 24 h 0.0 0.0 0.0 0.35 1.22 1.15
124331 BRD-K23875128 HEK293 0.37 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.34
124370 BRD-K23875128 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124439 BRD-K23875128 JURKAT 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.89 0.27
124500 BRD-K23875128 MDAMB231 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.11 0.92
124563 BRD-K23875128 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132510 BRD-K23875128 MCF10A 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132538 BRD-K23875128 MCF??7.00 0.25 uM 24 h 0.22 0.9 0.03 -0.37 -1.24 1.3
132628 BRD-K23875128 THP1 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).