CMap Candidate Details

Structure:
CMap ID: C00996
Pert ID: BRD-A40639672
Compound Name: ketorolac
Targets: PTGS1; PTGS2
MoA: Cyclooxygenase inhibitor
SMILES: OC(=O)C1CCn2c1ccc2C(=O)c1ccccc1
InchiKey: OZWKMVRBQXNZKK-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5516 BRD-A40639672 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
25291 BRD-A40639672 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37492 BRD-A40639672 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37815 BRD-A40639672 HEPG2 10 uM 6 h -0.25 -1.04 0.21 -0.26 -0.86 0.22
38342 BRD-A40639672 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38634 BRD-A40639672 PHH 10 uM 24 h 0.0 0.0 0.0 -0.38 -1.29 1.56
38855 BRD-A40639672 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123235 BRD-A40639672 A375 10 uM 24 h 0.24 1.0 0.1 0.0 0.0 0.0
123276 BRD-A40639672 HA1E 1.11 uM 24 h -0.2 -0.82 0.0 0.0 0.0 0.0
123312 BRD-A40639672 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123340 BRD-A40639672 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123397 BRD-A40639672 MDAMB231 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123421 BRD-A40639672 PC3 10 uM 24 h -0.22 -0.9 0.04 0.0 0.0 0.0
131550 BRD-A40639672 A549 2.22 uM 24 h -0.24 -1.01 0.16 0.0 0.0 0.0
131626 BRD-A40639672 HEK293 0.25 uM 24 h 0.28 1.16 0.36 -0.22 -0.74 0.05
131723 BRD-A40639672 HUVEC 0.74 uM 24 h -0.2 -0.81 0.0 0.0 0.0 0.0
131776 BRD-A40639672 JURKAT 2.22 uM 24 h 0.25 1.06 0.18 0.23 0.83 0.11
131823 BRD-A40639672 MCF10A 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131855 BRD-A40639672 MCF??7.00 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131933 BRD-A40639672 THP1 0.03 uM 24 h -0.27 -1.13 0.4 0.37 1.29 1.49
131952 BRD-A40639672 YAPC 2.22 uM 24 h 0.0 0.0 0.0 -0.26 -0.86 0.22
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).