CMap Candidate Details

Structure:
CMap ID: C09970
Pert ID: BRD-K23976833
Compound Name: travoprost
Targets: PTGFR
MoA: Prostanoid receptor agonist
SMILES: CC(C)OC(=O)CCCC=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1C=C[C@@H](O)COc1cccc(c1)C(F)(F)F
InchiKey: MKPLKVHSHYCHOC-AHTXBMBWSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
120891 BRD-K23976833 A549 0.125 uM 24 h -0.29 -1.21 0.6 -0.33 -1.12 0.94
120917 BRD-K23976833 HA1E 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120967 BRD-K23976833 HEK293 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121054 BRD-K23976833 MCF??7.00 1.11 uM 24 h 0.0 0.0 0.0 0.3 1.06 0.58
121124 BRD-K23976833 YAPC 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129100 BRD-K23976833 A375 0.25 uM 24 h 0.0 0.0 0.0 -0.22 -0.75 0.06
129154 BRD-K23976833 HELA 0.08 uM 24 h 0.22 0.93 0.05 0.0 0.0 0.0
129200 BRD-K23976833 HT29 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129226 BRD-K23976833 PC3 0.74 uM 24 h 0.19 0.79 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).