CMap Candidate Details

Structure:
CMap ID: C00998
Pert ID: BRD-A40787240
Compound Name: gemifloxacin
Targets: --
MoA: --
SMILES: CON=C1/CN(CC1CN)c1nc2n(cc(C(O)=O)c(=O)c2cc1F)C1CC1
InchiKey: ZRCVYEYHRGVLOC-HYARGMPZSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
123236 BRD-A40787240 A375 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123341 BRD-A40787240 HT29 0.04 uM 24 h 0.25 1.05 0.17 0.0 0.0 0.0
123365 BRD-A40787240 MCF10A 0.125 uM 24 h 0.0 0.0 0.0 -0.3 -1.03 0.62
123494 BRD-A40787240 YAPC 0.04 uM 24 h 0.3 1.27 0.58 -0.33 -1.13 0.97
131552 BRD-A40787240 A549 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131586 BRD-A40787240 HA1E 0.08 uM 24 h 0.0 0.0 0.0 -0.24 -0.79 0.11
131627 BRD-A40787240 HEK293 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131660 BRD-A40787240 HELA 0.01 uM 24 h 0.23 0.97 0.08 0.0 0.0 0.0
131724 BRD-A40787240 HUVEC 0.03 uM 24 h 0.0 0.0 0.0 -0.37 -1.24 1.3
131778 BRD-A40787240 JURKAT 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131857 BRD-A40787240 MCF??7.00 0.03 uM 24 h -0.24 -1.01 0.17 0.0 0.0 0.0
131891 BRD-A40787240 MDAMB231 0.01 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.55
131916 BRD-A40787240 PC3 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131934 BRD-A40787240 THP1 2.22 uM 24 h -0.26 -1.07 0.27 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).